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Product Information

About Recogen®
What is Recogen®?

Recogen® is a made in Germany 100% Bioactive Collagen Peptides (BCP) food supplement. Recogen® is pure protein and contains high concentrations of important joint building blocks, such as glycine and proline.


BCP is obtained by means of enzymatic hydrolysis of collagen-containing tissue from the bovine hides of healthy animals to help facilitate its absorption into the blood stream.The amino acid composition in BCP is similar to collagen and therefore helps to stimulate cartilage regeneration.

BCP is also an effective supplement that helps to nourish body tissues, cartilages, bones, tendons, ligaments, hair, nails and skin. 

Joint treatment methods

Recogen® is a premium brand developed and conceptualized by NCI. 

Recogen® is available in the following type:

  • Recogen® Original - 300g box - Contains NCI's proprietory blend of 100% pure bioactive collagen peptides 
  • Recogen® with Calcium - 30 days sachet pack - Comes in a box containing 30 x 10g sachets. Each sachet contains 9,000mg (9g) of bioactive collagen peptides and 1,000mg (1g) of Calcium lactate. The Calcium lactate used is obtained by fermentation of plant raw material (sugarcane). It is 100% made in Holland. The sachet pack is suitable for those who wish to have supplementation for both joint and bone.
  • Recogen® Gold - 300g box - Contains a synergistic blend of bioactive collagen peptides and rosehip extract. Dual action formula that helps to soothe joint pains and repair cartilage.


 

Why take Recogen®?

Our joints undergo a tremendous amount of stress over its lifetime. The stress placed on our joints means that they are prone to damage in the longer term as cartilage is worn out and sometimes even lost.

This "wear-and-tear" may lead to arthritic conditions such as osteoarthritis.

In a survey conducted by MOH and NUS in 2001, it was found that arthritic conditions and rheumatism are among the top 5 leading conditions for which treatment was sought in clinics in Singapore.

Osteoarthritis may be considered a degenerative disease, which inevitably occurs as the population grows older. Lack of exercise and being overweight are associated with an increased risk of osteoarthritis.

Modern dietary trends, including fast food, vegetarian diets and low fat & lean meat diets, mean that a large part of the population has inadequate intake of collagen.

Despite years of research, there is still no cure for osteoarthritis. At best, analgesics and anti-inflammatory drugs can relieve pain and suppress related inflammatory reactions. One method of providing a therapeutic approach is to focus on either providing means to inhibit the degradation of cartilage or to stimulate the biosynthesis of cartilage cells.
 
More and more scientific evidence suggest that our Bioactive Collagen Peptides stimulates the growth of Type II Collagen which is essential for the formation of joint cartilage.

If the following symptoms apply to you, try Recogen® today and feel the difference for yourself!

 
Symptoms to look out for:
• Pain when beginning a movement ("warm up" pain)
• Pain during exercise
• Restricted movement
• Tension in muscles and tendons
• Feeling of tension and stiffness in joints, particularly in the morning
• Swollen joints
• Grinding of the joints
• Increasing instability in the joint with local pain

 

The Recogen® difference

Recogen® contains the next generation ingredient, Bioactive Collagen Peptides, for jointcare supplements.  Recogen® has 3 unique advantages that separates it from other products: 

 
1. Extremely low molecular weight = Excellent absorption by body to reach targetted areas

Recogen® has an extremely low molecular weight of 3-6 kDaltons compared to 16,000 Daltons for some common glucosamine formulation. This is largely one of the reasons why Recogen® has worked so well for most people who have failed to see results with common glucosamine products.

 

2. Short peptide chains = Excellent absorption by body to reach targetted areas

The absorption rate of Recogen® by the body is enhanced as the long peptide chains of normal collagen are broken down via enzymatic hydrolysis into very short chains. 
 


 
 
 
 

3. Extensive scientific reports spanning over 30 years

The beneficial effect of Bioactive Collagen Peptides on joint health was first discovered in the 12th century, between 1098 to 1179 when Saint Hildegard of Bingen first described the beneficial effect of calf cartilage broth on joint pain. Since then there have been numerous scientific reports spanning over 30 years describing the beneficial effects of Bioactive Collagen Peptides.

 

 

How Recogen® works?

 

Watch how Recogen works
 


Recogen®'s effectiveness is based on the following factors:

1) Absorption rate and accumulation levels

Recogen® has a short peptide chain with extremely low molecular protein peptides content (approx. 3,000 daltons). With its excellent solubility, it is easily digested and absorbed into your body to increase the bioavailability of Type 2 collagen. 

 


2) Stimulation of Type 2 Collagen and proteoglycans production

Due to Recogen's Bioactive Collagen Peptide specific function, it helps to stimulate the production of type 2 collagen and proteoglycans. Type 2 collagen and proteoglycans form 90-95% of cartilage tissue. By increasing the production of type 2 collagen and proteoglycans, cartilage can regrow.
 

 



3) Reproduction of supportive joint tissue

Research indicates that Bioactive Collagen Peptide is not only readily and rapidly absorbed into the body system but also reaches the targeted joint tissue. In the presence of Recogen's Bioactive Collagen Peptides , the collagen production and regeneration of supportive tissue were both stimulated. This creates a positive change in the targeted joints. 
 

MRI images that shows how consumption of Recogen® helps boost cartilage growth.

 

 

Who needs Recogen®?

Recogen® is an ideal nutritional supplement for anyone wanting to stay fit and well as well as those who wishes to reduce their risk of degenerative joint disease by constitutional nutrition.

Recogen® will benefit:  

1) Those at risk of degenerative joint diseases such as:
a. Osteoarthritis
b. Skeletal deformity and abnormal joint position
c. Inflammatory joint diseases
d. Crystal-induce arthritis
e. Other metabolic or neurogenic diseases
f. Senior citizens
g. Individuals with traumatic injuries

2) Overweight individuals
 
3) Individuals whose occupational activities predispose to osteoarthritis, including jobs involving repeated knee-bending textile workers, miners and dock workers (e.g. carpenters, floor layers, and painters);
 
4) Individuals participating in extensive non-occupational physical activities including recreational runners/walkers, cyclists, gardeners, soccer/football players;
 
5) Individuals with a past history of significant joint injury such as fracture or ligamentous injury.
 
Safety Aspect

 

1) BSE Free. Not genetically modified

Recogen® is a food, NOT a drug. Recogen® contains 100% pure Bioactive Collagen Peptides (BCP) that is not genetically modified and free from Bovine Spongiform Encephalopathy (BSE,which causes Mad Cow Disease).

Every batch of Recogen® comes with a Veterinary Certification to certify it as BSE free. Recogen® does not contain any other additives and preservatives.


2) No Side Effects. Strong clinical evidence

Recogen® has NO SIDE EFFECTS. Recogen® is perfectly safe for long-term regular consumption and it's effectiveness in cartilage regeneration is backed by more than 20 years of clinical research.


3) Awarded GRAS status by U.S FDA

BCP was awarded GRAS (Generally Recognized As Safe) status by the U.S Food and Drug Administration (FDA) in 1999. BCP is recognized as a food additive in the EU and is still pending for status approval in Japan. 
 


4) Recognized by WHO

The "Bone and Joint Decade" was initiated by the World Health Organization (WHO) and the United Nations (UN) in order to improve the overall care and treatment of patients suffering from bone and joint diseases.

As BCP has particular benefits for joint health, it is a key focus of this inititative. For further information, you may visit www.boneandjointdecade.org

 
   

5) HALAL Certification

Recogen® is certified HALAL by MUIS Singapore and therefore safe for consumption amongst our Muslim consumers.


 
 

 




 

Nutrition Facts
Recogen® contains 100% Bioactive Collagen Peptides (BCP), obtained direct from Germany .

Recogen® is pure protein and thus free of fat & carbohydrates. Recogen® contains no chemical preservative and is soluble in cold liquids.

Its amino acid composition

Recogen® is a Bioactive Collagen Peptides (BCP) developed using patent technology - U.S. patent 4,804,745. Its amino acid composition is similar to the collagen found in human cartilage. By taking BCP, it will help to regenerate the growth of Type II Collagen.

In general there are 21 different types of collagen. Type II Collagen occurs almost exclusively in cartilage tissue. Native collagen and BCP differ in their amino acid composition. The biggest difference is in glycine and proline; in BCP, these are 3 times as high as in other protein. See amino acid comp graph below.

 


It is also interesting to compare the absolute amounts of amino acids in BCP and other protein-rich food. Based on grams of amino acid per 100g of BCP and food respectively the following ratios have bee established See graph on amino acid content below.

The table shows to obtain the same amount of glycine in 10g of Recogen®, you will need to take:

2.9L of milk or
164 g of pork

For the same amount of proline, you will need:

1.2kg of potatoes
140g of wheat bread

This comparison confirms that BCP provides the required amounts of the most important amino acids for the cartilage metabolism much more effectively and more selectively than any other protein containing food.

Extremely low molecular weight

BCP has an extremely low molecular weight of 3 to 6 kDaltons. Compared to normal gelatine with a molecular weight of around 100 kdaltons, it is easily absorbed into the blood stream

Recogen® and its biological Value

It is confirmed that Recogen® differs in its amino acid composition from other natural protein rich food. The graph below shows a comparison between Recogen® and the average occurrence of amino acid in natural protein-rich food. The natural protein-rich food refers to gelatine, milk Meat, potato, bread etc. The biggest differences are in glycine and proline; in BCP, these are 3 times as high as in other proteins.



However, it is not only the percentages but also the absolute amounts of amino acids in gelatine and other protein-rich food that are interesting and stand much in favor for BCP. Based on grams of amino acid per 10g of Recogen® and food respectively, the following ratios have been established as below.

The table shows that the consumption of About 2.8L of milk or 1.8kg of potatoes would be required to take in the same amount of glycine that is contained in 10g of Recogen®. The proline content in 10g of Recogen® is equivalent to 110g of meat, 1.2kg of potatoes or 140g of wheat bread.

Moreover Hydroxyproline which is particularly important for the selective collagen synthesis can only be detected in substaincial amounts in Recogen®.

 

Amino Acid Recogen® Milk Meat (Pork) Potato Wheat Bread
Alanine 8.7 0.12 1.53 0.11 0.24
Arginine 8.4 0.12 1.53 0.12 0.31
Aspartic acid 3.6 0.28 2.34 0.43 0.39
Cystine - - 0.31 - 0.2
Glutamic acid 6.7 0.75 3.9 0.46 3.15
Glycine 20.6 0.08 1.4 0.12 0.3
Histidine 0.6 0.09 0.99 0.04 0.18
4-Hydroxyproline 11.3 - - - -
Hydroxylysine 1.0 - - - -
Isoleucine 1.2 0.21 1.27 0.10 0.38
Leusine 3.0 0.35 1.92 0.14 0.59
Lysine 3.8 0.26 2.2 0.13 0.2
Methionine 0.6 0.08 0.72 0.03 0.13
Phenylalanine 2.3 0.17 0.98 0.10 0.42
Proline 14.0 0.35 1.21 0.11 0.96
Serine 3.3 0.19 1.1 0.10 0.39
Threonine 2.0 0.15 1.25 0.09 0.25
Tryptophan - 0.05 0.31 0.03 0.08
Tyrosine 0.5 0.17 0.91 0.08 0.21
Valine 2.8 0.23 1.42 0.13 0.39

Amino acid content in different food (1g amino acid per 100g food)
 

Scientific Evidence

Latest osteoarthritis research findings: Objective visual evidence that Recogen® promotes the regeneration of cartilage tissue.

This has been confirmed by the results of two independent investigations which were presented in September 2009 at the congress of the Osteoarthritis Research Society International (OARSI) in Montreal.  

A clinical trial performed by Harvard Medical School and Tufts Medical Center demonstrated the efficacy of Recogen® on the basis of magnetic resonance images (MRI). Working in collaboration with Kiel University, scientists at the Kiel-based Collagen Research Institute (CRI) then gathered experimental evidence of the effects of consumption of Recogen® on cartilage cells. 

Using an objective imaging technique, the Tufts researchers, led by Dr Timothy McAlindon, found a significant regeneration of the cartilage tissue in the Recogen® group, compared to normal cartilage degeneration progression in the placebo group. The CRI’s cell experiments indicated that Recogen® induces the increased synthesis of aggrecan (an important component in cartilage) and Type II collagen (which plays a key role in cartilage elasticity).

The role of Recogen® in the treatment and prevention of osteoarthritis
The administration of Recogen® can prevent joint degeneration and counteract load-induced wear of the articular cartilage. Compared to other substances which focus on providing short-term pain relief, Recogen® tackles the root causes of osteoarthritis and cartilage degeneration. Previous clinical trials had already shown that the substance promotes mobility and reduces pain.

Classified as a safe nutritional product by the FDA, Recogen® is easy to synthesize. Furthermore, thanks to its neutral taste and odour, Recogen® can be easily added to the individual’s daily diet. Positive health effects can be achieved even with low doses. Recogen® is suitable for all age groups with particular benefit for athletes (competitive and amateur), elderly persons and all health-conscious individuals who want to prevent cartilage degeneration at an early stage. 

OVER 30 YEARS OF RESEARCH 
The beneficial effect of Bioactive Collagen Peptides (BCP) was first discovered in the 12th century, between 1098 to 1179 when Saint Hildegard of Bingen first described the beneficial effect of calf cartilage broth on joint pain.
Investigator/Sponsor
Published
No. of patients
Study design
Krug/Heilit 1979 193 Open
Goetz/heilit 1982 60 Open
Oberschelp/Heilit 1985 154 Comparative
Seeliqmueller / Febena 1989 356 Open
Adam / Gelita 1991 82 double-blind, cross over
Seeliqmueller / Febena 1993 519 Open
Beuker, Eck/ Gelita 1996 40 Open
Beuker, Rosenfelf/ Gelita 1996 100 double-blind
Rippe / Nabisco * 250 double-blind
Moskowitz / Gelita 2000 389 double-blind
Adam / GELITA * 45 Comparative, double-blind
* denotes submitted for publication

Since 1980 scientists of different medical disciplines have strengthened their R&D activities in the field of both cartilage metabolism and the effect of Bioactive Collagen Peptides on joint health. There have been medical observations, key laboratory and clinical studies carried out over the past 20 years by internationally leading experts of different medical disciplines.

All clinical studies reveal positive effects of Bioactive Collagen Peptides on joint health, especially on osteoarthritis, for example: 
  • Significant reduction of pain
  • Reduced need for analgesics
  • Improvement of joint mobility
Landmark clinical studies: 
 
1991,
Professor Milan Adam
The most extensive research was carried out by Prof. Milan Adam, Professor of Rheumatology at the University of Prague , which led to the issue of a European patent, No 0254289 Agents for the treatment of osteoarthritis.

In his double blind study, (NOTE: A double blind study is a test procedure in which the identity of those receiving the intervention is concealed from both the administrators and the subjects until after the test is completed; designed to reduce or eliminate bias in the results) 82 participants were given either one of the following ingredients over a 16 month period.
  • Bioactive Collagen Peptides (Recogen®)
  • Gelatine
  • Gelatine + Glycine + Calcium Hydroxylate
  • Egg albumin
    (as placebo)
The result was a significant percentage of participants who reduced their need for analgesics after taking Bioactive Collagen Peptides.
   
1996,
Beuker & Rosenfeld
In the 1996 Beuker & Rosenfeld's double blind 6 months study, a significant percentage of the 100 elderly aged 65 years or greater shown improvement in joints mobility upon intake of Bioactive Collagen Peptides compared to those with placebo control.
   
2000,
Roland Moskowitz
Prof. Roland Moskowitz, Director of the Arthritis Research Institute, Cleveland/USA conducted an international study ( USA ; UK ; Germany ) with 390 patients suffering from osteoarthritis.
 
   
2003,
Steffen Oesser

 
In Spring 2003, Dr Steffen Oesser, physiologist at the University of Kiel, Germany published key studies on cartilage metabolism and regeneration; his latest publication (Cell & Tissue Research 311: 393-9; March 2003) demonstrated that Bioactive Collagen Peptides stimulates collagen biosynthesis in Collagen chondrocytes (cartilage cells). The presence of bioactive collagen peptides leads to dose-dependent increase of collagen type II Oesser et al. (Journal of Nutrition 129: 1891-95; 1999) conducted experiments with isolated segments of the intestine which have shown that collagen fragments can pass through the intestinal wall (10-15% of these proteins; in a high molecular form of up to 50kD) and reach the blood stream. Accumulation of radio-labelled bioactive collagen peptides can subsequently be seen in cartilage.
 
  



 

 

Recommendations

Dissolve Recogen® into plain water or any drink. For mild to moderate symptoms: Take 10 grams a day for a month followed by 5 grams per day. For severe symptoms: Take 10 grams a day for at least 3 months.

Do avoid adding Recogen® to boiling hot water as it will destroy the nutritional properties of Recogen®. Where possible, consume Recogen® in the morning as Recogen® can provide you with energy content to start the day.

Every box of Recogen® comes with 30 sachets. Use 1 sachet a day to get your required amount of Recogen®. 1 sachet = 10 grams of Recogen®.

Due to the constant breakdown and regeneration of collagen, research shows that symptoms may re-occur if use of the supplement is discontinued.

Where to buy?

You can purchase Recogen® by:

Click "here" to buy

  • Calling us at 6744 5566
  • Visiting our retail outlet at Block 3021 Ubi Avenue 2 #01-169 or
  • Through this website using your credit card

North:
Liew Chinese Physician Dispensary (Ang Mo Kio)
Block 163 Ang Mo Kio Avenue 4
#01-406 Singapore 560163
Tel: (65) 6457 8068
(Recogen and recoliv)

 

Central: 
Mother and Child Wellness (Orchard)
583, Orchard Road #02-34
Forum Shopping Mall
Tel: (65) 9658 8680
(Recogen and recoliv)

East:
Grace Healthcare Products Pte Ltd (Upper Changi)
Block 57A New Upper Changi Road 
#01-1380 Singapore 462057
Tel: (65) 6565 3593
(Recogen)

Grace Healthcare Products Pte Ltd (Tampines)
Block 829 Tampines Street 81 
#01-280 Singapore 520829
Tel: (65) 6788 4388
(Recogen)
 

West:
Grace Healthcare Products Pte Ltd (Bukit Batok)
Block 634 Bukit Batok Central 
#01-110 Singapore 650634
Tel: (65) 6565 3593
(Recogen)


Hui Min Medical Hall (Clementi)
Block 380 Clementi Avenue 5
#01-372 Singapore 120380
Tel: (65) 6777 0058
(Recogen)

 

To ensure you are getting the original products, follow the above methods to reach out to us. If you have any queries, call us at 6744 5566


 

 

Testimonial

Click on link to view actual written testimonials. We may edit or translate the actual testimonials to make it convenient for you to read. Please note a new window will pop up when you click on the link.


2014 - 2015 TESTIMONIALS

Mr Ron Wang, 29 years old (English text) - " I suffered knee pain when doing long distance run. For this reason, I'm not able to run for long distance for years. After consuming Recogen®, I tried longer distance run and my knee problem was solved like over night. I'm confident in the product and is back to purchase

Mdm Mary Lim Siew Noy, 71 years old (Chinese text) - " I injured my right arm after a fall. My friend recommended me Recogen® Gold. After consuming for a month, I went for a follow up with my doctor and my doctor told me I recovered very well. Now, I'm recommending Recogen® to my friends!"

Ler Noi Hiang, 67 years old (Chinese text) - " I was recommended to Recogen® by my friends. I've been trying painkillers and other supplements early on. Then I tried Recogen® Gold for a month and my knee pain has subsided. 

Nelson Ong, 54 years old (English text),  " I have fingers joint problem and within seven days only, the pain is gone. Recommended to wife and friends and feedbacks were good! Thank you!"

Mdm Lew Poo Chu, 57 years old (Chinese text)- " I've suffered from joints pain for a while already. A friend recommended Recogen® to me and I tried it for a week. After a week, my joint pains symptoms have improved."

Mdm Yap Siew Hua, 54 years old (Chinese text), "I'm suffering from pain in my neck for several months already. My friend gave me a can of Recogen® Gold and I tried it for a week. It worked for me and solved my neck pain."

 

2012 - 2013 TESTIMONIALS

Mdm Chang Yong Fei, 61 years old (Chinese text) " My knee hurts when going down the staircase. I saw Recogen®'s advertisement in the papers and bought 2 cans of Recogen Gold and Recogen® Original. After taking 1 can, the pain subsided and symptoms improved. Now I continue taking Recogen® to maintain my health."

Mr John Boon, 73 years old, (English text), "Since taking Recogen®, I am physically fit and still able to play and teach tennis."

Mdm Kwan Yin Leng, 55 years old (Chinese text), "I used to have pain in my knee joints and feet. After trying 1 can of Recogen®, the symptoms improved."

Ms Mandy Guan for her mother, Mdm Toh Meng Hoy, 53 years old (English text), "My mum started Recogen® for about 3 months. During the first 2 weeks when she has back and joint pain. She started with Recogen® Gold, the pain worsened for a few days but when she continue with the product, it reduces. When she finished her first can, she felt a difference in the body. No more back pain and joint does not product any more "noise" when she walks. She is now on Recogen® calcium to maintain a better and healthier life! Thank you Recogen®, as it really change my mum's life!"

Mr Desmond Goh, 56 years old (Chinese text), "My colleague recommended to me Recogen®. After trying it for a while, my joint pain symptoms have improved. I've been taking for 2-3 years and have recommended to many friends since.".

 

2010 TESTIMONIALS

Ms Chua Ser Lei, 22 years old (Chinese text) -  "My grandmother has been suffering from joint pains for many years. I was recommended to Recogen® by my colleagues. I bought one and now my grandmother can walk better. My grandmother now insists on taking Recogen® every day to improve her joints condition."
 
Ms Ling Lee Mui, 31 years old (Chinese text) - "My mother has been complaining about her joints pain problems for many years. I was recommended to Recogen® by my colleagues and bought one for my mum to try. After finishing the first can, she happily told me that her joints were not as painful as before and she continues to take Recogen® every day. So far, she has seen big improvements in her condition!"

Ms Wong Li Shan, Melody, 33 years old (English text) - "After taking Recogen® for a month, I started to walk with less pain."

Ms Azizah, 45 years old (English text) - "I've been taking Recogen® for about a month. I think it's good since the pain in my joints around the toes and knees has reduced."

Ms Loh Seng Yoon, 55 years old (Chinese text) - "My joints, hair and scalp have shown improvements! I drink Recogen®  everyday to protect my joints."

Mdm Lee Bee Sim, 56 years old (Chinese text) -  "My friend recommended Recogen® to me. I have taken Recogen® for close to three month and my joint pain condition has improved alot."

Ms Chua Lay Peng, 58 years old (English text) - "I was introduced to Recogen®  by a friend. We use the product for general health. The product improved my joints as well as helped with my hair growth."

Mr Arthur Allan Low, 59 years old  (English text) - "I've been suffering from joint and back pain for more than 10 years since I got into an accident years ago. I've tried so many medicine and also chinese acupuncture. But they don't work for me. I was recommended by my sister's to Recogen® . I've taken Recogen®  for 2 weeks and I feel so much better!"

Mr Steven Chew Kheng Moo, 61 years old (English text) - "My knees feel the pain when walking up the staircase. After taking Recogen®  for about a month, my knee problem is relieved and my legs feel 'lighter'. My stiff shoulders have improved and I can move my arms much better now."

Mr Lim Kee Chong, 63 years old (English text) - "After taking 2 cans of Recogen®, I feel my joint pains have reduced. I continue to take this product to keep my joints and bones healthy."

Mr G.W. Pereira, 65 years old (English text) - "I have been taking Recogen® for the past 8 months and it improved my osteoarthritic knee.."


Mr Roslan Bin Salim, aged 47, production supervisor

" Part of my job calls for squatting for long periods of time. Due to intense pain in my kneecaps, I could not squat completely. After taking Recogen® for three weeks, the pain is reduced considerably and I am able to squat down freely without pain."

Mr Ng Tian Sing, aged 74, former truck driver

" I was about to go through an operation for severe kneecap pain but after three weeks into taking Recogen®, the pain reduced significantly and the operation not necessary. I now take Recogen® for its continued benefits."

Mdm Low Gean Gean, aged 61, retired teacher

"As a teacher, standing during classes has been the cause of pain in my knees and joints. After just 14 days on Recogen®, my knees do not hurt as bad anymore and I can enjoy my retirement."

Mr Young Kok Wee, aged 56, civil servant

" I love exercising and sports, but kneecap pains have prvented me from working out. I have been taking Recogen® for three weeks now and I am back to my old rountine...without the pain of course."

Mdm Goh Siew Kee, aged 50, draftsman

Suffering pain at the kneecap and other joints for years. After taking Recogen® pain subsides significantly and able to move and twist body freely without feeling pain as experienced before.

Ms Lim Joo Huan, aged 39 

"Before using Recogen®, I always have problems with my skin. Over the years, I have tried using many brands of products - recommendations from close friends and family - none of them really worked for me. I was a little skeptical about Recogen® initially, thinking that it is "one of those products in the market". But after using it dilligently for 3 months, I noticed that my skin has gotten better. Even friends commented that I am looking more radiant and younger than ever. I am now a faithful patron of Reconge and will recommend everyone to use it."

Ms Jacqueline Goh, aged 26

"Over the years, I realized my skin was losing it's "glow". I decided to give Recogen® a try after some friends recommended it to me. I also made my DIY face mask using recogen and applied 2-3 times a week. After 2 weeks, I realized my skin was firmer and it was "glowing" from within. It  also helped my joint pains which I often suffer after a round of vigorous exercise. I am still consuming Recogen® everyday for its outstanding benefits."

...and many more satisfied Recogen® customers

 

FAQs
Q: I’m currently on medication, can I still take Recogen®?
A: Yes, you can. Recogen® is a food supplement with no known interactions with other foods or drugs.
 
Q: Is Recogen® a steroid or pain killer?
A: No. Recogen® is a food supplement not a drug.
 
Q: Are there any side effects?
A: There are no known side effects. Recogen® is safe for long term consumption. Because of its low molecular weight, it is easily absorbed through the intestinal walls without causing stomach irritation. Some clinical studies have reported increased flatulence and diarrhea but such cases are extremely rare and isolated.

The German Institute for Drugs and Medicinal Products, the Consumer Protection Ministry and the World Health Organization (WHO) have all confirmed the safety of bioactive collagen peptides.
 
Q: How safe is Recogen®?
A:  In 1999, the U.S Food & Drug Administration Department has granted the GRAS (Generally Recognized As Safe) status for Bioactive Collagen Peptides (BCP). A GRAS substance is one that has a long history of common use in foods, or that is determined to be safe based on proven science. Examples include your common salt, sugar, vitamins etc.
Q: Can Recogen® really stimulate cartilage regeneration?
A:Yes. It is already confirmed by 2 independent investigations presented in September 2009 at the congress of the Osteoarthritis Research Society International (OARSI) in Montreal. One study was conducted by Harvard Medical School and Tufts Medical Center. The other study was conducted by a collaboration of Kiel University and scientists at Kiel-based Collagen Research Institute (CRI). 
 
Q: I've started taking Recogen® for a few days and I’m experiencing more pain in several areas of my body. Should I stop taking Recogen®?
A: The fact that some people may perceive more pain in the initial phase of taking Recogen® is not related to the product but to the “ups and downs” of pain in osteoarthritis. Some days, you may feel fine and, then, after a few days, you may feel worse again. Several clinical studies have proven the effectiveness of Recogen® against osteoarthritis, so continue to take Recogen® as per normal. If you experience pains not related to osteoarthritis, you may like to confirm with a medical doctor on your condition before taking Recogen®. 
 
Q: I don't experience pain in my joints. Can I still take Recogen®?
A: Definitely! Everyone's joints go through wear and tear throughout our lifetime. Taking Recogen® early and regularly helps slows down the wear and tear process and decreases the risk of osteoarthritis when you get older. It is highly recommended to incorporate a good diet and active lifestyle together with supplements.
 
Q: Why is the sachet 10g but it doesn't completely fill the scoop that comes with the loose powder can?
A: Calcium lactate is denser than bioactive collagen peptides powder. Each sachet contains 1000mg of Calcium lactate with 9,000mg of Bioactive Collagen Peptides.
 
Q: What is the type of Calcium used in the sachet box?
A: We use Calcium lactate derived from plants. It is easily soluble and dispersible in water with a neutral taste.
  
Q: Can I mix Recogen® in coffee and tea?
A: We do not recommend coffee and tea. Fruit juices, honey and most other beverages are suitable.
 
Q: I've been taking Recogen® for about 1 month now and I don't feel any much better?
A: Results varies across individuals due to different physical conditions. If you have serious symptoms, continue to take Recogen®, for at least up till 6 months. In the event that you are not experiencing the benefits of Recogen®, here's a checklist:

Confirm you have osteoarthritis. Recogen® don't work well for muscular aches, damaged nerves etc.
·       Consume the recommended dosage of 10g a day
·       NEVER mix in HOT beverage as it will affect the effectiveness of Recogen®. Cold and warm beverage is recommended.
·       Consume everyday for best results
  
Q: Is the product “heaty”?
A: There is no documented incident amongst our numerous clinical studies on “heatiness”. Again, this depends of individuals and it's still an isolated incident.
 
Q: Will I gain weight by taking Recogen®. Are there fats content?

A: Consumption of Recogen® has no effects on weight increase or dietary imbalance. Recogen® is a protein comprising only amino acids, water and minerals and contains no fat, carbohydrates or preservatives.
 

Q: When is the best time to consume Recogen®? In the day or before bedtime?
A: Generally there is no fixed rule on when is the best time. You can take it any time of the day that is most convenient to you. However as Recogen® is a protein dietary supplement, it can help provide energy to the body. We do recommend adding Recogen® to your breakfast for a more nutritional diet.
 
Q: Can pregnant women, children consume Recogen®?
A: There are no restrictions on its use. Adolescents, pregnant women, manual workers, diabetics, obese people and all who do not have protein metabolism problems, problems of elimination or other rare diseases can take it without risk.
 
Q: Can someone with Parkinson and/or suffering from kidney stones consume Recogen®?
A: There is no know evidence that Recogen® interacts with Parkinson or kidney stones.

Morbus Parkinson is caused by a lack of dopamine without any connection to bioactive collagen peptides. Kidney stones are made of concretions of urine. Recogen® do not contain any uretic proteins that can cause kidney stones. We advise customers who has any existing illnesses to always consult your medical doctor before starting on any types of food supplements.

Q: I'm taking glucosamine, can I consume Recogen® together with glucosamine?
A: Yes, you can take them together. However we do not recommend this as you will not have a clear indication which product has greater efficacy. Usually we would recommend taking Recogen® by itself over a period of at least 1-3 months and observe the results.
 
Q: I'm taking medications for osteoporosis, can I consume Recogen® as well?
A: Yes, you may do so, thus far, Recogen® do not have any adverse interactions with current medications available in the market. However we do advise to always seek advice from your medical doctor prior to intake.
Q: Why is Recogen® only available online and at your Ubi Avenue 2 outlet?

A: By selling online and at our dedicated outlet, we are able to servce our customers better. We are able to offer better pricing, better service and the convenience of home delivery. The "traditional" method of selling through local pharmacies outlet may be convenient to some customers but we chose to pass on the savings from not listing our products at these outlets to our customers.

Customers are also overwhelmed by the different types of product on display and no good sales person can guide the customer towards selecting a suitable product.

Q: Why don't you add Vitamin C, pro-biotics, other extracts etc to your formulation?

A: Unless there is enough evidence that there is synergy in effectiveness by combining different ingredients, we would preferably still keep to 2-3 ingredients in our formulation. We do not add the latest ingredients just because it is popular in the industry. We scrutinize the clinical studies and efficacy of every ingredient we come across. We will also assess the manufacturer's credibility before deciding whether it is good enough for our customers. And of course, before that, we at NCI would try out the products first.

 

 

 

About Recogen® Gold
What is Recogen® Gold?

Recogen® Gold is a brand new premium product from NCI that offers extra joint health protection for you!

Recogen® Gold is a synergistic Double Action formula, combining collagen hydrolysate and rose hip extract. Collagen hydrolysate helps regenerates cartilage while rose hip extract has anti-inflammatory and analgesic effects.

Rose hip extract (like collagen hydrolysate) is a very safe ingredient with no side effects. In studies conducted in Germany, the use of rose hip extract helped to reduce inflammation in the joint areas by as much as 50%. Rose hip extract also helped decrease enzymes that aid in cartilage degradation.

How Recogen® Gold works?

Inflammation is actually a normal body response to injured areas. During normal inflammation, chemicals from leukocytes (or white blood cells) help protect the body from infections. However, sometimes due to autoimmune disorder, leukoctes can cause excessive damage to the affected areas.

Recogen® Gold helps inhibits cytokines distribution in the affected areas, therefore helping to reduce inflammation.

 

 




 

Clinical Studies

Clinical Study 2010

Study Objective: Testing for efficacy, tolerability / acceptance / adverse effects and fast pain relief. Study was conducted at Regio Kliniken, Germany in 2010.

Study details:

  • Total of 50 subjects (58% female, 42% male)
  • Age (in number of years): 60.6 +/- 11.9
  • BMI range: 29.7 +/- 5.6
  • Osteoarthritis grade: 3.0 +/- 0.8 (At grade 3.0 there is cartilage loss and subject has difficulty walking and exercising

Study design: Daily oral application of 5.5g of Recogen® Gold over 12 weeks

Measurements: WOMAC scores - pain, stiffness, activities and composite (total scores)

Results: Clinical data showed a clear improvement in more than 75% of subjects after a 12 weeks Recogen® Gold therapy. Subjects have shown improved mobility as well as reduction in pain during activity and at rest.

Recogen® product chart

Different products give different functions. Choose the Recogen® to suit your needs.

FAQs

 

Q: Can I take Recogen® Gold with other Recogen® products?

A: Yes, you may do so. However the recommended dosage is 10 grams a day. Any additional dosage above 10 grams do not guarantee extra or faster results.

Q: Can I take my painkillers together with Recogen® Gold?

A: Yes, you can. Recogen Gold has no known interactions with existing medications available on the market. However, we would advise customers to always seek advice from their medical doctors prior to intake of any supplements.
 
Q: Can I stop taking my painkillers once I start on Recogen® Gold?

A: Recogen® Gold takes time to take effect. We would recommend customers to continue taking their painkillers when they start on Recogen® Gold. Recogen® Gold can reduce the symptoms fast or slow in patients therefore patients should observe if the symptoms are reduced. However, we would advise customers to always seek advice from their medical doctors prior to intake of any supplements.
 

 

Recogen® For Sportsperson
FAQs

 

Q: I take part in marathons and other sporting activities, how will Recogen®  benefit me?


A: Recogen® is an excellent food supplement for the daily maintenance of your joint cartilage. For individuals who are active in what we term as "high impact" sports, the joints areas undergo severe stress and will wear out faster over time if not properly looked after. Consumption of Recogen® on a regular basis will help maintain your joint cartilage health to prevent osteoarthritis in the near future.

Recogen® itself is a pure protein and contains high levels of amino acids like glysine, proline and hydroxyproline. The consumption of Recogen® can help provide a certain amount of energy content to your body prior to starting your sporting activity.
 
Q: I am not experiencing any pain in my knees area, should I take Recogen®?

A: Yes. In fact the earlier the better because sportsperson (especially regular cyclists and runners) expose their knees to heavy wear and tear due to the impact of the sports. You may not feel the pain now but over a prolonged period, with the cartilage wearing off, you will pay the price for neglecting your joint health.
 
Q: Recogen® contains collagen, isn't it for women who wants to improve their skin?

A: Recogen® contains 100% pure bioactive collagen peptides. Other than benefits for the skin, it is an effective supplement in the prevention against osteoarthritis. In fact, bioactive collagen peptides is recognized by the World Health Organization (WHO) to be beneficial against osteoarthritis. As collagen is the main building block of our body system, consumption of Recogen® can help improve overall health of individuals.
 
Q: Any scientific proof? What about young active adults, can they consume Recogen®?

A: Yes. The latest published report is in the 2008 by Penn State University*.  The study was conducted over a period of 24 weeks period involving 147 (72 males, 75 females) athletes. The 147 athletes was split into 2 groups: 1 group consumed 25 ml of liquid drink containing 10g of bioactive collagen peptides, another group consumed a 25 ml liquid drink containing xanthan gum. 
 
The results showed that the ingestion of bioactive collagen peptides over a period of 24 weeks helped to reduce the symptoms of joint discomfort effectively.

* Clark Kristine L, Sebastianelli W, Flechsenhar KR, et al., 24 week study on the use of collagen hydrolysate as a dietary supplement in athletes with activity-related joint pain. Curr Med Res Opin. 2008 May; 24(5): 1485-96.
 
Another significant study result released in September 2009 has shown that consumption of Recogen® can help stimulate growth of cartilage tissues. You can read more under the news section. Click here.
 
About Osteoarthritis
What is OA?

Osteoarthritis is a degenerative joint disease characterized by progressive destruction of joint cartilage and associated structures such as bone, synovial and fibrous joint capsule and the periarticular musculature.

Cartilage damage always arises from a disparity between the ability on the part of joint cartilage to cope with stress and the actual stress applied. There are 2 basic forms of osteoarthritis: Primary & Secondary.

Primary . Actual cause unknown. Genetic predisposition, tissue weakness, nutritional anomalies within the bradytrophic joint cartilage and other similar general factors have been considered; however a clear trigger has not yet been identified.

Secondary . Consequence of previous damage or of another illness. Such as 

  1. Overuse injuries
  2. Post-traumatic change
  3. Inflammatory & age-independent joint disease
  4. Systemic, metabolic and endocrine disorders
  5. Neurological disease
  6. Joint disease during growth phase, including post-traumatic and post infectious disorders of growth
  7. Congenital development disorders and joint deformities
The Situation

 

In USA , the number of people between the ages of 75 and 85 doubled in the two decades between 1960 and 1980; those over the age of 85 has increased by 140 %. The United States National Health and Nutrition Examination Survey (NHANES 1, 1988 - 94) found that 79 percent of men and 86 percent of women between the ages of 75 and 79 suffered from osteoarthritis of the hand. 

The Framingham Study - a long-term study conducted by the National Institutes of Health in the USA since 1948 - found evidence of osteoarthritic knee conditions in one third of those studied in the age group 63-94.

  • An English study published in 2001 (Peat et al.) showed that degenerative knee changes resulting in functional impairment occurred in 10 percent of those over 55 years of age. The symptoms and impairments were classified as being severe in one-fourth of these patients.
  • In Singapore , it is estimated that 30% of people over the age of 65 have arthritis, in particular, those of degenerative type.

Survey revealed that 6% of the adult population has significant joint or muscles aches. Most common forms of arthritis are osteoarthritis and rheumatoid arthritis, which affects about @24,000 Singaporeans. As much as 25% of people with arthritis don't do anything to relieve their symptoms.

A survey on primary medical care conducted by MOH and NUS in 2001, it was found that arthritic conditions and rheumatism are among the top 5 leading conditions for which treatment was sought in primary private and public medical care clinics in Singapore . They are accounted for 4.8% of the total attendance.

Based on National Health Surveillance Survey 2001:

: Prevalence of reported arthritis according to gender and age groups (2001)

 

Age (Years)
Male (%)
Female(%)
Of Total Population(%)
18 – 24
0.5
-
0.3
25 – 44
1.2
1.5
1.4
45 – 64
3.1
8.2
5.7
65 – 74
9.3
21.4
15.6
〉75
16.7
28.9
24.2
18 岁以上
2.6
5.7
4.1

 

 
2: Prevalence of reported arthritis according to gender and racial groups (2001)
Racial Group 
Male (%)
Female(%)
Of Total Population(%)
Chinese
2.9
5.4
4.2
Malay
1.3
6.8
4.1
Indian
1.2
6.9
4.0
  • Approximately 1 in 25 (4.2%) Singaporean aged 18 years and above are dignasoed with arthritis. Females (5.7%) had a higher prevalence of reported arthritis than males (2.6%).
  • 3 major ethnic groups has about the same prevalence of reported arthritis (4.2%-Chinese, 4.1 - Malay & 4.0-Indians). 5.6% of elderly aged 65-74 years and 24.2% of elderly aged 75 years and above are diagnosed with this problems.  
  • 5.6% of elderly aged 65-74 years and 24.2% of elderly aged 75 years and above are diagnosed with this problems.  


 Based on National Health Surveillance Survey 2007: 

: Prevalence of reported arthritis according to gender and age groups (2007)

 

 

Age (Years)
Male (%)
Female(%)
Of Total Population(%)
18 – 29
4.5
5.3
4.9
30 – 39
6.2
9.0
7.6
40 – 49
8.5
13.8
11.2
50 – 59
9.6
15.8
12.7
60 – 69
18.0
21.4
19.8
18 – 69
8.2
11.9
10.1

 

2: Prevalence of reported arthritis according to gender and racial groups (2007)

 

Racial Group 
Male (%)
Female(%)
Of Total Population(%)
Chinese
8.0
12.0
10.0
Malay
8.7
10.0
9.3
Indian
9.5
14.5
11.9

 

·         Compared to 2001's survey results, for the group aged 18 - 69 years old, the prevalence of reported arthritis's percentage has doubled within these 6 years.
 

 

 

The Reason
  • The increased life expectancy is one reason for the rising incidence of osteoarthritis in industrialized countries.

    •  Numerous epidemiological studies conducted since the 1970s have shown that there is a correlation between osteoarthritis and being overweight. In obese people, degenerative joint diseases occur significantly more frequently than in people of the same age of normal weight.
     

In Singapore , the 1998 National Health Survey, based on the WHO criteria (normal weight: BMI 18.5-24.9; overweight: BMI 25.0-29.9; obese: BMI 30 and above) found that in adults (aged 18 to 69 years), 24.4% were overweight and 6.0% were obese; thus, 30.4% were above the normal weight. There were slightly more obese Singaporean females (6.7%) than Singaporean males (5.3%). The highest proportion of obesity was found in the 50-59 years age group.

  • Lack of exercise
  • Incorrect and excess strain on cartilage: a result of occupational demands, performance sport or postural anomalies.
  • Additional risk factors for primary and secondary osteoarthritis are traumatic injuries, repetitive and severe mechanical stress, abnormal joint positions, neuropathic changes, dysplasia and genetic factors including several hereditary diseases such as hemophilia, hemoglobinopathy or congenital dislocation of the hip.
  • Changes in food consumption patterns. There are also more people going "greens" or eating more lean meat. Thus the collagen in-take from the daily food is insufficient to maintain or increase the synthesis of the cartilage.
  • Lack of collagen in daily food intake. Weight watchers who go greens and those who take only lean meat do not have sufficinet collagen in their body.
     
The Consequence

Today, there is still no cure for osteoarthritis. At best, pain can be relieved, related inflammation suppressed and further functional impairment delayed.

Current treatments for osteoarthritis are physiotherapy,nonsteroidal anti-inflammatory drugs and local glucocorticoid crystal injections.

Surgery is only possible in certain joints and is considered a last resort because of the costs, the stress placed on the patient and the surgical risks involved.

With the growing number of patients, the progressive causes and the socio-economic impact of the disease, it is reasonable to pursue promising options in the prevention and therapy of osteoarthritis.

Taking preventive steps before the onset of irreparable degeneration is necessary. However this is difficult in cases where there are no symptoms. It also requires intensive patient motivation, counseling, and education.

Appropriate preventive measures include lifestyle changes (loss of weight, moderate physical exercise, avoidance of excessive joint strain) and the timely treatment of abnormal joint positions, infections, and other risks.

Adequate intake of certain nutrients to optimize specific metabolic processes in (blood vessel-free!) cartilaginous tissue is an additional promising approach.

Medical recommendations for preventive measures must be practical and be adopted by the patient. Unrealistic advice, e.g. drastic behavior change or time consuming and expensive therapies, is likely to fail.

Metabolism and Turnover

Cartilage consists of cellular building blocks - the chondrocytes - and an extracellular specific matrix, which is of particular physiological significance. The extracellular matrix of the cartilage contains two classes of macromolecules: proteoglycans (such as aggrecan) which are responsible for the compressive strength and elasticity of the tissue and collagen (Type II Collagen fibrils) that provides its tensile and shear strength.

Cartilage, like bone, is subject to a continuous, slow regenerating process. There are numerous matrix metalloproteases (such as collagenase, stromelysine, aggrecanase), as well as lysosomal proteases (cathepsins), which can degrade all cartilage building blocks at neutral pH.

According to current understanding, the activity is controlled by the cytokine interleukin-1. A tissue inhibitor of metal metalloproteases and a plasminogen activator inhibitor are antagonists that inhibit the catabolic enzymes, thus slowing down cartilage degradation.

There are also polypeptide mediators, which, as growth factors, stimulate anabolic metabolic processes in cartilage, thus contributing to cartilage formation to a limited extent. This group of mediators includes the extent. This group of mediators includes the insulin-like growth factor 1 and the transforming growth factor ? both of which stimulate proteoglycan synthesis. Recent results have shown that collagen fragments such as those contained in bioactive collagen peptides can function as mediators stimulating the synthesis of cartilage matrix (Oesser et al., 2003). However, their activation requires an adequate supply of the appropriate building blocks proline and glycine.

Signs of Osteoarthritis

The most frequent symptom is the pain. However, this is not an early symptom. As joint cartilage has no nerve fibers, the pains signals periarticular structure are involved.

Joint pain is generally described as a deep, dull, continuous type of pain restrictioned to a joint and its immediate environment. It occurs on movement but not at rest.

Symptoms such as:

•  Brief intial pain, normally occuring after intensive or abonormal stress on the joint,
•  Pain when beginning a movement ("warm-up" pain)
•  Fatigue pain
•  Stress pain (pain during exercise)
•  Constant pain
•  Night pain
•  Local muscle pain (tension in muscles and tendons)
•  Restricted movement
•  Swollen joints
•  Grinding of joints
 

Consequently..

Healthy cartilage is subject to continuous turnover as a result of anabolic and catabolic processes. For the anabolic (growth) phase, the necessary building blocks must be available in adequate quantities.

Due to the specific properties of Collagen Hydrolysate, it may be a relevant intervention in the causative process of osteoarthritis.

In addition to biochemical regulators, physical factors (e.g. physical and athletic stress) also affect cartilage metabolism. Static and continuous stress inhibit the synthesis of proteoglycans and proteins, whereas moderate stress of relatively short duration promotes the biosynthesis of matrix building blocks. While adequate amounts of physical activity and joint movement preserve cartilage, overexertion and continuous stress can give rise to pathological changes.

A patient's lifestyle plays a major role in the prevention of degenerative cartilage disease. In addition to protecting against abnormal stress, an optimal supply of the building blocks required for cartilage metabolism and tissue formation is necessary, whether in the form of food or as a nutritional supplement.

Importance of Collagen

Collagen represents about 30% of mammalian protein content and has a very specific amino acid composition. The triple helical collagen molecule consists of about 1,000 glycines, 360 prolines and 300 hydroxy-prolines; the latter do not occur in any other protein. The human body can synthesise main collagen. But an enormous quanitites must be made available.

There are 21 different collage types. However Type II Collagen is the most important collagen for maintaining a healthy cartillage.

About Bone K+
FAQs

Can children take Bone K+? How much can they take?

Bone K+ is specially formulated for age 14 & above.  However, if you have younger children from 2 – 13 years old, consider giving them on alternate days instead of daily.

The naturally rich Omega 3 in krill oil helps enhance their brain growth and promotes development of their eye, joint and nervous system. Vit. D & K given at alternate days are within the recommended intake of that age.

It is always advisable to consult with your paediatrician before administering Bone K+ to them.

Can I break open the soft gels and consume?

Breaking open the soft gels is never advisable.

How should I store my krill oil?

Bone K+ should be stored in a cool, dry place. Avoid direct sunlight or heat. Refrigeration is not required.

Who should take Bone K+?

Bone K+ is formulated for anyone who is age 14 & above and desires to maintain healthy bones & joints.

  • Highly recommended for growing teens where bone formation is crucial.
  • Those with high risk of bone loss:
  1. Elderly. Bone loss begins around age 30-40.
  2. Postmenopausal women
  3. Smoking & high intakes of alcohol individuals.
  • Those with bone problems such as low bone density, osteoporosis, bone fracture etc.
  • Individuals with insufficient Omega 3 fatty acids, Vit D & K2 in their daily food intake.

How safe is Bone K+? 

The U.S. Food & Drug Administration (FDA) confirmed the GRAS (Generally Recognized As Safe) status for Krill Oil.

European Food Safety Authority, EFSA, has approved vitamin K on its health claim for building and maintaining healthy bones.

Bone K+ is a dietary supplement, not a drug. It is safe for regular long-term consumption if direction of use is followed.

When is the best time to consume Bone K+?

For best absorption, consume Bone K+ once a day with a meal.

How long before I see any effects?

Results vary across individuals. We recommend daily consumption of Bone K+ for optimal bone and joint health benefits.

Are there any side effects?

There are no reports of any side-effects for long-term consumption if direction of use is followed.

Can I take Bone K+ with Recogen?

Yes, you can take Bone K+ with Recogen. You will have a complete bone & joint care health supplement. Bone K+ reduces joint inflammation and improves of bone development. While Recogen helps you to regenerate your joint cartilage.

Can I stop my fish oil after taking Bone K+?

Yes, you should replace your fish oil product with Bone K+. Besides having higher EPA & DHA than fish oil, our krill oil’s unique molecular composition which is rich in phospholipid (omega-3 fatty acid) and astaxanthin surpasses the profile of fish oil.  It’s shown to be more efficiently accumulated in the blood and in target organs.

Is there any fishy aftertaste and burps after taking Bone K+?

No. As our krill oil is a phospholipid omega-3 based oil, it dissolves in water and mixes well with stomach fluids. Whereas fish oil forms a layer of oil in the stomach. Hence you will not experience any fishy aftertaste and burps with Bone K+.

How can Bone K+ alleviate joint pain and arthritis problems?

Bone K+ consists of high potency Krill Oil, Vitamin D and K.  Our proprietary blend aims to support & comfort bone and joints. Astaxanthin, a powerful antioxidant naturally found our krill oil, protects the body against free radicals. Daily intake of Bone K+, may reduce pain, stiffness and inflammation arise from osteoarthritis and rheumatoid arthritis.

Addition of Vitamin D & K enhances calcium absorption and aids in building strong bones.

I am on aspirin/warfarin; can I still take Bone K+?

We highly recommend you to consult a healthcare professional prior to taking if you are taking a blood thinner medication. 

I am allergic to shellfish; can I still take Bone K+?

No. We do not advise you to take Bone K+ if you are allergic to shellfish as Bone K+ contains the krill (crustacean).

Can I take Bone K+ during pregnancy & breastfeeding?

Although Bone K+ has an excellent safety profile, it has not been tested in this group. We recommend you to consult your doctor before taking any supplements.

Is Bone K+ suitable for pets?

Yes! Dogs suffer the same problems as humans, including joint health, heart health and cognition, especially for aged dogs (and cats). So there is much sense in adding krill oil to the food of cats and dogs

Clinical Studies

Bone K+ benefits the joints health through the following clinical studies:

Clinical Studies 1 :
Study details:  
Population: subjects with slightly increased inflammation (CRP>1)

Study groups:   
Group A: Placebo   
Group B: Bone K+ 

Study duration and design:
DB, PC, R study of 4 weeks supplementation 

CRP= C-reactive protein, DB= Double Blind, PC = Placebo Control, R= Research

Measurements:
CRP and WOMAC scores (pain, stiffness, functional impairment) at baseline and days 7, 14 and 30 

Results:

Consumption of Bone K+ : Reduce Inflammation


Source: Deutsch L. J Am Coll Nutr. 2007 Feb;26(1):39-48.

Consumption of Bone K+: Reduces Joint Pain


Source: Deutsch L. J Am Coll Nutr. 2007 Feb;26(1):39-48.
# score between 0 and 4, 4 being the worst pain


Consumption of Bone K+: Reduces Joint Stiffness


Source: Deutsch L. J Am Coll Nutr. 2007 Feb;26(1):39-48.
#score between 0 and 4, 4 being the worst pain 


Consumption of Bone K+: Reduces Functional Impairment


Source: Deutsch L. J Am Coll Nutr. 2007 Feb;26(1):39-48.
# score between 0 and 4, 4 being the worst pain

 

Clinical Studies 2 :

Newly Published Study Highlights the benefits of Bone K+ for mild Knee Pain

Population: 50 adults (38-85 YO) with mild knee pain

Study groups: 
Group A: Placebo   
Group B: Bone K+ 

Study duration and design: 
DB, PC, R study of 4 weeks supplementation  

DB= Double Blind, PC = Placebo Control, R= Research

Measurements: Subjective measures of knee pain according to two Japanese arthritic questionnaires*

*questionnaires used in the study mainly test effect of knee pain on daily functions.

Results:
The following functions improved only in Bone K+ group:

  • Waking up at night due to pain
  • Pain when ascending stairs
  • Pain when standing
  • Walking on a flat surface
  • Putting on socks
  • Doing heavy housework
  • Limitations on daily activities

Source: Suzuki et al, PLoS One. 2016​

Bone K+ Difference

The increase in omega-3 index is doubled when consumption of Bone K+ krill oil as compared to fish oil

Source: Ramprasath et al, 2013

What is Astaxanthin?

Astaxanthin is a potent antioxidant naturally found in krill oil extracts from krill. It is a carotenoid with powerful scavenging ability for lipid and free radicals.  Thus protecting the cell against oxidation and the damaging effects of free radicals. This “super antioxidant” has been found to beneficial to the eye & skin health.  It is also well known for its anti-inflammatory and pain reliever properties.

Nutrition Facts

Serving size: 2 Soft Gels (1 Krill oil & 1 Vitamin Soft Gel)

Servings per Box: 30

 

Amount Per Serving

 Calorific Value

3 kcal

 Krill Oil

500 mg

 Phospholipids

210 mg

 Eicosapentaenoic (EPA)

75 mg

 Docosahexaenoic (DHA)

45 mg

 Omega 3 – Fatty acids

150 mg

 Astaxanthin Esterified

750 mcg

 Vitamin D3 (cholecalciferol)

600 IU

 Vitamin K-2 (MK-7)

90 mcg

Bones & Joints

Bones

Bones protect our internal organs from impact damage. They are living tissues that rebuild constantly throughout our life. It is estimated that we replace about 10% of skeletal bone tissue every year. In our growing years, the formation of new bones is faster than bone loss - resorption.

However, from late 30s – 40s, the rate of resorption is faster than bone formation. There’s a vast decrease in bone mass and density after menopause. It is necessary to build strong bones when you are young and prevent bone loss when you are older.

 

Joints

Joints are places that connects the bones. Together with bones, they allow body movement. Healthy bones & joints are essential for maintaining mobility in your life.

Vitamin D & Vitamin K

Vitamin D

Vitamin D plays an important role in the regulation of calcium and maintenance of phosphorus levels in the blood. These two factors are crucial for maintaining healthy bones. Vitamin D absorbs calcium in the intestines and otherwise it will be excreted through the kidneys.

The current recommended daily allowance (RDA) is 600 IU for those 1-70 years of age. Vitamin D deficiency has been seen in up to 80% of hip fracture patients. Deficiency is common, especially in the elderly, infants, people with darker complexion and people living at higher latitudes or who get little sun exposure.

Vitamin K

Vitamin K is a fat-soluble vitamin occurs naturally in 2 forms. Vitamin K1 is found in plants; Vitamin K2 can be found in high fat dairy products, meat and fermented soy beans, natto.  Vitamin K2 is the more important nutrient in preventing calcium loss. Unfortunately, many of the best food sources of vitamin K2 also are high in saturated fat. To obtain the amount of Vitamin K2 in Bone K+, you need to consume 2250g of lamb.

Binds calcium and other important minerals to your bones. There are many remarkable studies about Vitamin K2 being effective in reducing bone loss and retaining bone strength, thereby preventing osteoporosis:

Many studies published in Osteoporos Int.  conclude that Vitamin K2 reverses bone loss and increases bone mass in some people with osteoporosis. A recent study, published in Osteoporos Int. 2015 March, conducted on 6759 participants has shown the importance of Vitamin K2 in maintaining and improving vertebral Bone Mineral Density (BMD) as well as preventing fractures in postmenopausal women with osteoporosis. Another 2-year study on 241 women with osteoporosis showed 84% reduction in bone loss for women receiving both calcium & Vitamin K2 when compared to those who had only calcium.

Numerous Japanese trials show that Vitamin K2 supplementation produces 60% reduction in vertebral fractures, 77% reduction in hip and 81% reduction in other non-vertebral fracture. Prevents hardening of the arteries, a common factor in coronary artery disease and heart failure. While adhering calcium to your bone, Vitamin K2 also inhibits calcium from depositing in our artery. Thus preventing calcification in our coronary arteries, reducing the risk of cardiovascular disease.

What is good for strengthening your bones?

Calcium, Vitamin D and K is good for strengthening your bones

Your bone strength depends on more than just calcium. Together with Vitamin D and K2, they form the tri-essential to bone health.

Studies lead by Mr. Iwamoto J, published in Keio J Med. 2003 Sep & J Orthop Sci. 2000, have indicated that the combination of Vitamin D3 and Vitamin K2, compared to single supplementation of calcium, Vitamin D or Vitamin K2, showed the largest increase in new bone development.

About "recoliv" - Anti-aging collagen
What is "recoliv"?

recoliv is the all-natural collagen product formulated with the most potent antioxidants found in olives and grapes. The collagen found in recoliv can slow down processes that impair your skin's metabolism, thus improving skin elasticity and firmness.
 

With new German technology, the collagen has undergone a special enzymatic treatment to produce specific bioactive collagen peptides which optimizes the stimulation of fibroblasts in the skin. Having an extremely low molecular weight of 2 kdaltons, it is easily absorbed and delivered directly into the dermis, which systematically increases collagen production.

Clinical Studies

 

“recoliv” uses collagen that is a composition of different specific collagen peptides derived from a special hydrolysis of bovine type I collagen with an average molecular weight of 2.0 kDaltons.

Figure 1: Detection of labelled “recoliv” collagen peptides in skin over 192 hours after one single oral application

Accumulation of recoliv collagen

In several scientific experiments the potential of “recoliv” collagen for skin cell metabolism and skin beauty from within was investigated. Previous bioavailability studies demonstrated that collagen peptides could be detected in different organs and connective tissues after oral administration [1].

[1] Oesser S, Adam M, Babel W, Seifert J. Oral administration of (14)C labeled gelatin hydrolysate leads to an accumulation of radioactivity in cartilage of mice (C57/BL). J Nutr 1999; 129 1891-5

 

Figure 2: Skin elasticity increased significantly after oral “recoliv” collagen treatment in comparison to placebo administration.

Figure 3: Skin elasticity was statistically significantly increased by “recoliv” collagen treatment. 

Figure 4: Long-lasting Effect on Skin Elasticity 4 weeks after End of Treatment 

Figure 5: Skin Moisturizing Changes in Women aged 50 years and above, 4 weeks after End of Treatment 

Source: Skin Pharmacology and Physiology 
Volume 27, Pages 47-55, doi: 10.1159/000351376
“Oral Supplementation of Specific Collagen Peptides Has Beneficial Effects on Human Skin Physiology: A Double-Blind, Placebo-Controlled Study”
Authors: E. Proksch, D. Segger, J. Degwert, M. Schunck, V. Zague, S. Oesser

FAQs
I’m on medication, can I take recoliv?

"recoliv" has no known interaction with any medical drugs. It is safe for consumption. If you have a pre-existing medical condition, always consult your medical doctor prior to consuming any supplements.

"recoliv" contains any medication?

No. "recoliv" is a food supplement. There’s only collagen hydrolysate, olive and grape extract.

There are other brands using collagen, olive and/or grape extract, how is "recoliv" different?

Our collagen hydrolysate is made using latest German technology where we obtain collagen that is optimized for the skin. Our collagen hydrolysate also has a molecular weight of 2kDalton, making it very easily absorbed by the body. Most products uses olive leaf or grape seed extracts. We extract from the entire fruit to obtain a total anti-oxidant profile.

Any side effects?

"recoliv" is a food supplement using natural extracts and ingredients that have been known for a long time. There is no evidence that long term consumption will have any side effects.

How safe is "recoliv"?

NCI only selects ingredients that meet our stringent criteria. Our collagen hydrolysate is made in Germany and we use olive and grape extract from France. Our suppliers and packing facilities are HACCP and ISO certified. Recoliv also uses ingredients that have GRAS (Generally Recognized As Safe) status.

What’s the proof that recoliv really works?

You can visit www.recoliv.com for clinical studies information.

When is the best time to take recoliv?

Where possible, we generally recommend taking recoliv either in the morning or afternoon as the collagen hydrolysate gives some energy to start the day. There is no harm taking recoliv in the evening.

How to consume recoliv?

Simply open a sachet and add to a cup of water or your favourite beverage.

Why are there dark purplish sediments when I added to water?

These sediments are natural and a result of extract from the entire grape itself. Some extracts in the market uses only the seeds or skin, but in our case, we extract from the whole fruits to obtain a total polyphenol profile for the best antioxidant properties.

Why 5g a day?

Our studies have shown that at 5g a day, the skin receives the optimal benefits. At more than 5g a day, there is no significant additional improvements from consuming recoliv. Key clinical studies results will be published soon.

What is the difference between Recogen collagen and recoliv collagen?

Both are collagen hydrolysate but they are unique in terms of bioactivity. Recoliv uses a special bioactive collagen peptide that is optimized for the skin whereas Recogen’s bioactive collagen peptide is optimized for the joints. This is achieved by new German technology that uses specific enzymes to obtain optimized collagen for the skin.

Can I add recoliv to coffee and tea?

We generally don’t recommend adding recoliv to caffeinated drinks or alcohol for best results. You can still drink your coffee and tea after consumption of recoliv.

Why bovine vs fish collagen?

The reason recoliv uses bovine collagen hydrolysate is because of it’s tasteless and odourless profile. Compared to fish collagen which usually has a “fishy” odour, bovine collagen hydrolysate is easy to drink and generally better accepted by most individual.Also cows are closer to human body’s structure, generally the body tend to accept ingredients made from bovine source better.

Is recoliv "heaty"?

As recoliv contains collagen hydrolysate, which is a protein, it is considered “heaty”.

Will I gain weight?

No. Taking recoliv will not cause weight gain.

If I have diabetes, high blood pressure and/or high cholesterol, can I still take recoliv?

Yes, you can continue taking recoliv. Recoliv is suitable for anyone with the mentioned condition. If you have a pre-existing medical condition, always consult your medical doctor prior to consuming any supplements.

Can pregnant lady or children take recoliv?

Pregnant ladies and children should always consult your medical doctor prior to consuming any supplements.

 

Testimonials

Ms Watt Wai Kheng, 62 years old, "After consuming for 3 months, my face became radiant and skin also became firmer. My friends also commented that I look prettier and my skin is not so dull."

Ng Su Peng, 28 years old, "This is by far, the only collagen product that has worked for me. After consuming for one month, my skin has become significantly smoother and moisturized. Makeup stays longer. I like it that the ingredients are natural and there are no added sugar that makes the taste artificial."

Regina Quek, 60 years old, "I have been taking recoliv for 2 months and I found the results amazing. It has helped to improve my skin condition after consumption. My joints have been more supple whereas in the past, I experienced pains around my shoulder and neck areas. My skin used to be dry even though I used lotion. Surely recoliv has helped me tremendously and I would recommend it to those who have skin and joints problems."

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